White matter microstructural abnormalities related to emotional dysfunction and childhood trauma characterize adolescents with borderline personality disorder.

Yi, Xiaoping; Wang, Xueying; Shen, Liying; Fu, Yan; Xiao, Qian; Zhang, Jinfan; Ding, Jun; Jiang, Furong; Zhang, Zhejia; Grecucci, Alessandro; Chen, Bihong T

doi:10.1007/s11682-025-01046-1

White matter microstructural abnormalities related to emotional dysfunction and childhood trauma characterize adolescents with borderline personality disorder.

2025-08-11, Brain imaging and behavior (10.1007/s11682-025-01046-1) (online)
Xiaoping Yi, Xueying Wang, Liying Shen, Yan Fu, Qian Xiao, Jinfan Zhang, Jun Ding, Furong Jiang, Zhejia Zhang, Alessandro Grecucci, and Bihong T Chen (?)

The neurobiological mechanism underlying adolescent borderline personality disorder (BPD) remains unclear. This study aimed to assess white matter (WM) microstructural abnormalities associated with emotional dysfunction and childhood trauma in adolescents with BPD.

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White matter microstructural abnormalities related to emotional dysfunction and childhood trauma characterize adolescents with borderline personality disorder.